Five home-care formulas and one professional protocol for oily, congested and breakout-prone skin — working on the stress signal that drives the oil, not just the oil itself.
Arriving September 2026 — have your routine prescribed at a SKEYNDOR+ salon.
Under pressure, skin makes more cortisol — the stress hormone. Cortisol is where the oil, the congestion and the breakouts begin.
For fifty years, we treated the smoke. CLEARIST CTX reaches the fire — cortisol, the one point everything else ignores.
Congestion and breakouts have four drivers in the pore. CLEARIST CTX answers every one.
When the cells lining the pore over-produce, they obstruct it — the first step toward congestion.
Androgens drive excess oil and shine. The enzyme 5-alpha reductase is the switch that keeps it flowing.
The bacteria behind breakouts are normal residents — until an oil-rich, blocked follicle lets them proliferate and inflame.
Blockage, altered oil and bacteria trigger inflammation — and, over time, marks and recurrence.
Fresh, non-comedogenic textures — each built for a step in the day, and prescribed for your skin.
Step 1 · CleanseUnclogs and gently exfoliates in one step — lifting oil and impurities, easing shine, no tightness. AM & PM.
Step 2 · DayRegulates oil without drying — purifying from the first use. GABA works needle-free to refine pores and hold back shine. AM.
Step 2 · NightA gentle daily peel (10% AHA) that refines pores and softens the look of marks — with an anti-cortisol action from Tephrosia. PM.
Step 3 · HydrateThe hydrator — rebalances barrier and microbiome, calms skin unsettled by acids or vitamin-A, and finishes matte. AM & PM.
Targeted · SOSDab onto a single blemish. Dries fast, forms an invisible film like a patch, and helps it fade without marks. Anytime, up to 3× daily.
Your therapist reads your skin and builds the exact routine. Find a salon to have yours prescribed.
Find a salonSame cleanse, same finish — the middle step changes with the light.
Aesthetic-medicine mechanisms meet the science of psychodermatology. A few of the actives at work:
The botanical the CTX is named for. It regulates how skin cells make cortisol — the driver of oil and inflammation, and the one point everything else ignores.
GABA is a neuro-relaxing amino acid that eases oil to the surface — needle-free. Sarcosine quiets 5-alpha reductase, the enzyme behind over-production.
Instead of stripping the skin, it trains the skin's own antimicrobial defences — reinforcing innate immunity against breakout bacteria.
An anti-androgenic, antibacterial 5-alpha reductase inhibitor — regulating oil and calming the environment breakouts thrive in.
Mandelic, succinic, glycolic and gluconolactone (PHA). Low-solubility acids concentrate inside the pore — refining texture with minimal irritation.
Lens esculenta normalises how pore-lining cells mature and shed, so oil flows freely — visibly refining the appearance of enlarged pores.
Twice across the course, the routine goes professional — an hour under the DermaLED canopy, blue light to purify at the surface, red to calm and restore below. The half a jar can't give you.
VISIA and VISIOSCAN imaging on 21 people — young and adult — with blemish-prone, oily and combination skin. Five weeks on the complete protocol.
Instrumental study, 21 volunteers, combination/oily blemish-prone skin. Five weeks of the complete CLEARIST CTX protocol — the home-care range plus two in-salon treatments with DERMALED XPERT. VISIA skin analysis; sebaceous activity by VISIOSCAN VC 20 PLUS + SEBUFIX. Results refer to the full protocol, not to any single product. Cosmetic treatment — not a medical therapy.
Before
After
The same skin on the complete CLEARIST CTX protocol — home-care range plus in-salon sessions. Individual results vary.
Have your skin read and your routine prescribed at a SKEYNDOR+ salon — then keep it going at home with the range.